The clinical spectrum of reactions developed based on paraphenylenediamine hypersensitivity two pediatric cases

393 Paraphenylenediamine (PPD) is a blue-black aniline dye commonly used in hair dyes. It is also used in textile and fur dyes, wool dye, dark cosmetics, temporary tattoo hennas, photo baths, and photocopy and printing ink. Paraphenylenediamine, which accelerates the absorption of hair dye and henna tattoos by the skin and helps the formation of the black color, is an allergen. Paraphenylenediamine leads to hypersensitivity reactions, involving allergic and irritant contact dermatitis [1–3]. Since tattoo and hair dyes are now frequently used in younger children, complications of these applications (which are considered harmless and temporary) are appearing in children. In this study, two pediatric patients who presented to our department with clinical symptoms similar to angioedema and allergic contact dermatitis are discussed. Case 1: A 9-year-old boy presented with redness, itching, swelling and burning sensation in his right arm. In the preliminary case history, he stated he had received a temporary tattoo performed with Indian henna on his right arm 3 days before. There was no atopy history of either the patient or his family. He had no systemic or dermatological illnesses. On the dermatological examination, erythematous and edematous papulonodular plaques in the tattooed area of the right arm were observed (Figure 1 A). Other systemic findings and laboratory tests were within normal limits. He was diagnosed with allergic contact dermatitis based on the temporary Indian henna tattoo and prescribed topical corticosteroid for 5 days and oral desloratadine 5 mg/day for 5 days. The lesions improved without sequelae within a short period of time (Figure 1 B). Letter to the Editor